Guillermo Rocamora was born in Uruguay in 1981. He studied Media Studies at Uruguay’s Republic University, and Screenwriting at the International Film and TV School in Cuba. He also participated in the literary workshop of author Mario Levrero. In 2004, he wrote and directed his first fiction short film, Connections, and in 2007 he co-wrote and directed with Javier Palleiro the short film Good Trip (Official Selection Cannes 2008).

Guillermo is the co-writer and director of the feature-length film Solo, premiered in the 30th Miami International Film Festival in 2013 (Best Opera Prima). In 2013, he wrote and directed the documentary The Essence of Carolina Herrera de Baez for the Discovery Channel. In 2014, he directed a documentary series about Colombian drug lord Pablo Escobar for Fusion TV (USA). He is the director of the documentary Freedom is a Big Word, selected for the IDFA 2018. He is currently working on the financing of his next fiction work Temas propios.